Bio-molecular NMR Facility
Protein NMR projects, fragment-based screening and natural products NMR.
What they do
- Services
- Protein NMR projects
- Fragment-based screening
- Natural products NMR
- Medicinal chemistry support
- Metabolomics
- Routine NMR
- Structure verification
- Data collection and processing
- Sample preparation advice
- Bio-fluid data collection
- One-dimensional experiments
- Two-dimensional experiments
- 1D NMR techniques
- 2D NMR techniques
- Non-uniform sampling
- Ligand screening
- Protein-detected screening
- 1H detection
- 19F detection
- HTS hit assessment
- Backbone resonance assignments
- Side chain assignments
- Dynamics studies
- Structure determination
- Multi-point titrations
- 400–700MHz field strengths
- 800 MHz access
- Cryogenic NMR probes
- Automated experiments
- Fragment libraries
- Liquid handler
- High-capacity autosampler
- 1H and 31P capability
- Sample tube accommodation
- Protein NMR systems
- Low-concentration binding
- Nucleic acid NMR
The HMS Bio-molecular NMR Facility provides access to small and large molecule solution state NMR spectroscopy in support of chemical and structural biology. Source (opens in a new tab)