Developmental Therapeutics Core
Preclinical experiment design, in vivo tumor biology and in vitro tumor biology.
What they do
- Services
- Preclinical experiment design
- In vivo tumor biology
- In vitro tumor biology
- Efficacy models
- Toxicology assessment
- Immunization and antibodies
- Animal protocol write-ups
- Surgical expertise
- Tissue processing
- Monoclonal antibody production
- Experimental design consultation
- Pharmacokinetics analysis
- Device implantation
- IC50 determination
- Cell proliferation assays
- Apoptosis assays
- 3D cultures
- Organoid cultures
- Caliper measurements
- IVIS imaging
- Estrous cycle monitoring
- Vaginal plug evaluation
- Sperm assessments
- Maximum tolerated dose
- Drug administration
- Stereotactic surgery
- Primary mouse DRG cultures
- 160+ cancer cell lines
- Subcutaneous xenografts
- Orthotopic xenografts
- Syngeneic mouse models
- Tumor metastasis studies
- PDX assistance
- Humanized mouse models
- Animal procurement
- Device toxicity assessment
- Monoclonal antibody capability